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After being cleaved by the gamma and beta secretases the amyloid beta peptide, which has about 40 amino acid residues, leaves the membrane, changes shape and aggregates into long fibrils. These fibrils form dense plaques on nerve cells.

After being cleaved by the gamma and beta secretases the amyloid beta peptide, which has about 40 amino acid residues, leaves the membrane, changes shape and aggregates into long fibrils. These fibrils form dense plaques on nerve cells.

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